The Effect Of Pillbox Use In Increasing Patients' Adherence To Type 2 Diabetes Mellitus Therapy in Lubuk Kilangan Health Center

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Najmiatul Fitria
Khairatul Husnia
Fahira Tri Ananta
Yelly Oktavia Sari


Patient Adherence, Type 2 diabetes mellitus, medication, adherence


Adherence is the extent to which the patient takes the medication as determined by the health care provider. The success of a patient's therapy is strongly influenced by adherence to the use of the drug. Low adherence to therapy is a particular problem in patients with diabetes mellitus. Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels, which cause damage to the heart over time, vasculature, eyes, kidneys, and nerves. The pill count method was used by calculating the rest of the drug from the patient to assess the patient's level of adherence. Objective: Adherence assessments are carried out through the Home Medication Review program. This study aimed to determine the differences in therapy adherence of patients with type 2 diabetes mellitus using the pill count method. Method: This type of research is experimental with pretest-posttest control group design research. This method is selected because the calculation of the rest of the drug is carried out before and after the intervention is given. Sampling in this study uses the total sampling method. The data was taken from Chronic Disease Management Program patients with type 2 diabetes mellitus treated at the Lubuk Kilangan Padang Health Center for January-March 2022. There are two groups of patients: patients with and without pillboxes. The data analysis used in this study is the Mann-Whitney Test. Result: The results showed a difference in the level of therapeutic adherence between the pillbox group and those who did not use the pillbox, with a value of p = 0.000 (p<0.05). Conclusion:It can be concluded that the level of adherence is higher in patients who use pillboxes than in those who do not.

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1. Blenkinsopp A, Bond C, Raynor DK. Medication reviews. Br J Clin Pharmacol. 2012;74(4):573-80. j.1365-2125.2012.04331.x
2. Chandrasekhar D, Joseph E, Ghaffoor FA, et al. Role of pharmacist led home medication review in community setting and the preparation of medication list. Clin Epidemiol Glob Heal. 2018;7(1):66-70.
3. Seuring T, Marthoenis, Rhode S, et al. Using peer education to improve diabetes management and outcomes in a low-income setting: a randomized controlled trial. Trials. 2019;20(1):548.
4. Sari YO, Fitria N, Mariza W, et al. Application of Home Medication Review ( HMR ) on Patient Adherence in Type 2 Diabetes Mellitus ( T2DM ) Blood Sugar Management. 2022;160-7.
5. Intenational Diabetes Federation. IDF DIABETES ATLAS Ninth edition 2019. Https://Www. Idf. 2019
6. Al-Azemi N, Diejomaoh MF, Angelaki E, et al. Clinical presentation and management of diabetes mellitus in pregnancy. Int J Womens Health. 2013;6:1-10.
7. Anna V, van der Ploeg HP, Cheung NW, et al. Sociodemographic correlates of the increasing trend in prevalence of gestational diabetes mellitus in a large population of women between 1995 and 2005. Diabetes Care. 2008;31(12):2288-93. https://doi. org/10.2337/dc08-1038
8. Tim Rikesdas 2018. Laporan Provinsi Sumatera Barat Riset Kesehatan Dasar Tahun 2018. Badan Penelitian dan Pengembangan Kesehatan. 2018.
9. Okatch H, Beiter K, Eby J, et al. Apparent antiretroviral overadherence by pill count is associated with HIV treatment failure in adolescents. J Acquir Immune Defic Syndr. 2016;72(5):542-5.
10. Grymonpre RE, Didur CD, Montgomery PR, et al. Pill count, self-report, and pharmacy claims data to measure medication adherence in the elderly. Ann Pharmacother. 1998;32(7-8):749-54.
11. Pharmacy Program Administrator. Program rules Home Medicines Review. Australian Government Department of Health; 2021.
12. Campbell Research & Consulting. Home Medicines Review Program Qualitative Research Project Final Report. Department of Health & Ageing Medication Management & Research Section. 2008.
14. Schwartz JK. Pillbox use, satisfaction, and effectiveness among persons with chronic health conditions. Assist Technol. 2017;29(4):181-7.
15. Dinas Kesehatan Kota Padang. Profil Kesehatan Tahun 2020. Padang: Dinas Kesehatan Kota Padang; 2021.
16. Fitria N, Idrus L, Putri AR, et al. The usability testing of the integrated electronic healthcare services for diabetes mellitus patients during the pandemic in Indonesia. Digit Heal. 2023;9:20552076231173228.
17. Fitria N, Sari YO, Putry AR, et al. Future challenge on probiotics uses from fermented milk on the endocrine disorder in human. IOP Conf Ser Earth Environ Sci 2021;888(1)012047.
18. Fitria N, Sari YO, Ananta FT, et al. Adherence Assessment on Hypertension Therapy Using The Pill Count Method in Lubuk Kilangan Health Center , Indonesia | Apr N. 2023;69-75.
19. Culig J, Leppée M. From Morisky to Hill-bone; self-reports scales for measuring adherence to medication. Coll Antropol. 2014;38(1):55-62.
20. Wells JCK. The New “Obstetrical Dilemma”: Stunting, Obesity and the Risk of Obstructed Labour. Anat Rec. 2017;300(4):716- 31.
21. Waugh N, Royle P, Clar C, et al. Screening for hyperglycaemia in pregnancy: a rapid update for the National Screening Committee. Health Technol Assess. 2010 Sep;14(45):1-183.
22. GBD. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet (London, England). 2015 Jan;385(9963):117-71.
23. Mawaw PM, Yav T, Mukuku O, et al. Prevalence of obesity, diabetes mellitus, hypertension and associated risk factors in a mining workforce, Democratic Republic of Congo. Pan Afr Med J. 2017;28:282.
24. Rao SS, Disraeli P, McGregor T. Impaired glucose tolerance and impaired fasting glucose. Am Fam Physician. 2004 Apr;69(8):1961- 8.
25. Purba FD, Hunfeld JAM, Iskandarsyah A, et al. Quality of life of the Indonesian general population: Test-retest reliability and population norms of the EQ-5D-5L and WHOQOL-BREF. PLoS One. 2018;13(5):1-20. pone.0197098
26. Soewondo P, Ferrario A, Tahapary DL. Challenges in diabetes management in Indonesia: a literature review. Global Health. 2013;9:63.
27. Hassan MH, Abd-Allah GM. Effects of metformin plus gliclazide versus metformin plus glimepiride on cardiovascular risk factors in patients with type 2 diabetes mellitus. Pak J Pharm Sci. 2015;28(5):1723-30.

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