Awareness, knowledge, and behaviour of Jordanian public regarding misuse and overuse of proton pump inhibitors

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Mariam Ahmad Alameri
Lobna Gharaibeh
Mai I. AL-Hawamdeh
Randa Atwan
Enas Daoud


proton pump inhibitors (PPIs/PPI), awareness, knowledge, behaviour web-based survey, Jordan


Background: Proton pump inhibitors (PPIs) are frequently used for the treatment and prophylaxis of upper gastrointestinal tract disorders. PPIs are now frequently the first-choice treatment for people with diseases associated with acidity. Objectives: The aim of this study is to assess the awareness, knowledge, and behaviour of the Jordanian public regarding the misuse and overuse of proton pump inhibitors. Methodology: The survey was made with Google Forms and made available online through various social media channels. Using a practical sample technique and the snowball dissemination of the questionnaire, participants were recruited. Adulthood and residence in the Hashemite Kingdom of Jordan were requirements for inclusion. Results: A total of 418 participants responded and filled out the questionnaire, with an average age of 37.5 ± 14.2 years. almost one third experienced a GI disease, n = 115 (27.5%), but around half of the participants, 204 (48.8%), used at least one type of PPI. 88 (43.1%) of the participants who used the PPIs experienced vitamin B12 deficiency as the most frequent side effect. The knowledge score was calculated for participants; the overall knowledge score was very low (2.8/8); the lowest score was on the correct duration for PPI use (0.13/1). In the multivariate analysis, predictors of a higher score of knowledge were working in a medical field and a monthly income lower than 500 JD. Conclusion: Findings from this study demonstrated that the overall knowledge score for Jordanians was low, which indicates that the Jordanian public is unaware of the PPIs correct use and possible side effects. Hence, with the dramatic increase in PPIs use, educational initiatives and programs are required to enhance public knowledge, particularly among those with non-medical educational backgrounds and monthly income above 500 JD.

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