The association between social support and medication adherence in patients with hypertension: A systematic review
Main Article Content
Keywords
Social Support, Medication Adherence, Health Personnel, Hypertension, Outcome Assessment, Health Care, Systematic Reviews as Topic, Australia
Abstract
Background: Medication adherence is a primary determinant of treatment success in hypertensive patients. One of the challenges for healthcare providers that has received little attention is the impact of patients’ social supports on medication adherence.
Objective: This review evaluates the impact of patients’ social supports on medication adherence in hypertensive patients.
Methods: A systematic review methodology was used. Pubmed, CINAHL, Embase, and PsycINFO databases were searched systematically for relevant articles. The outcome measure in the studies was medication adherence in hypertension.
Results: From 1155 articles, 238 were retained for further assessment, and finally, 14 met the inclusion criteria. Statistically significant positive associations between medication adherence and social support were found in nine studies (p<0.05).
Conclusions: This review evaluated the impact of social support on medication adherence and highlighted gaps in the literature regarding the impact of social support on adherence. Family members or peer support may promote better adherence in some patient groups. This review suggests that healthcare providers may need to consider whether patients have appropriate social supports in place which will assist them adhering to and benefiting from treatment recommendations.
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References
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10. Adisa R, Olajide OO, Fakeye TO. Social Support, Treatment Adherence and Outcome among Hypertensive and Type 2 Diabetes Patients in Ambulatory Care Settings in southwestern Nigeria. Ghana Med J. 2017;51(2):64-77.
11. Costa Rdos S, Nogueira LT. Family support in the control of hypertension. Rev Lat Am Enfermagem. 2008;16(5):871-876. https://doi.org/10.1590/s0104-11692008000500012
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15. Stopford R, Winkley K, Ismail K. Social support and glycemic control in type 2 diabetes: a systematic review of observational studies. Patient Educ Couns. 2013;93(3):549-558. https://doi.org/10.1016/j.pec.2013.08.016
16. Bosworth HB, Olsen MK, Neary A, et al. Take Control of Your Blood Pressure (TCYB) study: a multifactorial tailored behavioral and educational intervention for achieving blood pressure control. Patient Educ Couns. 2008;70(3):338-347. https://doi.org/10.1016/j.pec.2007.11.014
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18. Magrin ME, D'Addario M, Greco A, et al. Social support and adherence to treatment in hypertensive patients: a meta-analysis. Ann Behav Med. 2015;49(3):307-318. https://doi.org/10.1007/s12160-014-9663-2
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21. Olowookere AJ, Olowookere SA, Talabi AO, et al. Perceived family support and factors influencing medication adherence among hypertensive patients attending a Nigerian tertiary hospital. Ann Trop Med Public Health. 2015;8(6):241-245.
22. Khadoura K, Shakibazadeh E, Mansournia MA, Aljeesh Y, Fotouhi A. Determining the Prevalence of and the Factors Associated with Antihypertensive Medication Non-Adherence in the Gaza Strip. Korean J Fam Med. 2021;42(2):150-158. https://doi.org/10.4082/kjfm.19.0081
23. Haidari A, Moeini M, Khosravi A. The Impact of Peer Support Program on Adherence to the Treatment Regimen in Patients with Hypertension: A Randomized Clinical Trial Study. Iran J Nurs Midwifery Res. 2017;22(6):427-430. https://doi.org/10.4103/ijnmr.ijnmr_16_16
24. Shen Y, Peng X, Wang M, et al. Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China. J Hum Hypertens. 2017;31(1):29-36. https://doi.org/10.1038/jhh.2016.8
25. Hacihasanoglu Asilar R, Yildirim A, Saglam R, Demirturk Selcuk E, Erduran Y, Sarihan O. The effect of loneliness and perceived social support on medication adherence self-efficacy in hypertensive patients: An example of Turkey. J Vasc Nurs. 2020;38(4):183-190. https://doi.org/10.1016/j.jvn.2020.07.003
26. Pladevall M, Brotons C, Gabriel R, et al. Multicenter cluster-randomized trial of a multifactorial intervention to improve antihypertensive medication adherence and blood pressure control among patients at high cardiovascular risk (the COM99 study). Circulation. 2010;122(12):1183-1191. https://doi.org/10.1161/circulationaha.109.892778
27. Uchmanowicz B, Chudiak A, Uchmanowicz I, Rosińczuk J, Froelicher ES. Factors influencing adherence to treatment in older adults with hypertension. Clin Interv Aging. 2018;13:2425-2441. https://doi.org/10.2147/cia.s182881
28. Spikes T, Higgins M, Quyyumi A, Reilly C, Pemu P, Dunbar S. The Relationship Among Health Beliefs, Depressive Symptoms, Medication Adherence, and Social Support in African Americans With Hypertension. J Cardiovasc Nurs. 2019;34(1):44-51. https://doi.org/10.1097/jcn.0000000000000519
29. Criswell TJ, Weber CA, Xu Y, Carter BL. Effect of self-efficacy and social support on adherence to antihypertensive drugs. Pharmacotherapy. 2010;30(5):432-441. https://doi.org/10.1592/phco.30.5.432
30. G/Tsadik D, Berhane Y, Worku A. Adherence to Antihypertensive Treatment and Associated Factors in Central Ethiopia. Int J Hypertens. 2020;2020:9540810. https://doi.org/10.1155/2020/9540810
31. Hatah E, Lim KP, Ali AM, Mohamed Shah N, Islahudin F. The influence of cultural and religious orientations on social support and its potential impact on medication adherence. Patient Prefer Adherence. 2015;9:589-596. https://doi.org/10.2147/ppa.s79477
32. Kurniawati ND, Wahyuni ED, Toulasik YA. Family support improves hypertensive patient drug compliance. Indian J Public Health Res Develop. 2019;10(8):2660-2665.
33. Wallston BS, Alagna SW, DeVellis BM, et al. Social support and physical health. Health Psychology. 1983;2(4):367-391. https://doi.org/10.1037/0278-6133.2.4.367
34. Kaplan RM, Hartwell SL. Differential effects of social support and social network on physiological and social outcomes in men and women with type II diabetes mellitus. Health Psychol. 1987;6(5):387-398. https://doi.org/10.1037//0278-6133.6.5.387
35. Smith EMJ. Ethnic Minorities: Life Stress, Social Support, and Mental Health Issues. The Counseling Psychologist. 1985;13(4):537-579. https://doi.org/10.1177%2F0011000085134002
36. DiMatteo MR. Social support and patient adherence to medical treatment: a meta-analysis. Health Psychol. 2004;23(2):207-218. https://doi.org/10.1037/0278-6133.23.2.207
2. Abebe SM, Berhane Y, Worku A, Getachew A. Prevalence and associated factors of hypertension: a crossectional community based study in northwest ethiopia. PLoS One. 2015;10(4):e0125210. https://doi.org/10.1371/journal.pone.0125210
3. Ashoorkhani M, Majdzadeh R, Gholami J, Eftekhar H, Bozorgi A. Understanding Non-Adherence to Treatment in Hypertension: A Qualitative Study. Int J Community Based Nurs Midwifery. 2018;6(4):314-323.
4. Gwadry-Sridhar FH, Manias E, Lal L, et al. Impact of interventions on medication adherence and blood pressure control in patients with essential hypertension: a systematic review by the ISPOR medication adherence and persistence special interest group. Value Health. 2013;16(5):863-871. https://doi.org/10.1016/j.jval.2013.03.1631
5. Gast A, Mathes T. Medication adherence influencing factors-an (updated) overview of systematic reviews. Syst Rev. 2019;8(1):112. https://doi.org/10.1186/s13643-019-1014-8
6. McQuaid EL, Landier W. Cultural Issues in Medication Adherence: Disparities and Directions. J Gen Intern Med. 2018;33(2):200-206. https://doi.org/10.1007/s11606-017-4199-3
7. Cooper LA, Roter DL, Johnson RL, Ford DE, Steinwachs DM, Powe NR. Patient-centered communication, ratings of care, and concordance of patient and physician race. Ann Intern Med. 2003;139(11):907-915. https://doi.org/10.7326/0003-4819-139-11-200312020-00009
8. Turan GB, Aksoy M, Çiftçi B. Effect of social support on the treatment adherence of hypertension patients. J Vasc Nurs. 2019;37(1):46-51. https://doi.org/10.1016/j.jvn.2018.10.005
9. Ford ME, Tilley BC, McDonald PE. Social support among African-American adults with diabetes. Part 1: Theoretical framework. J Natl Med Assoc. 1998;90(6):361-365.
10. Adisa R, Olajide OO, Fakeye TO. Social Support, Treatment Adherence and Outcome among Hypertensive and Type 2 Diabetes Patients in Ambulatory Care Settings in southwestern Nigeria. Ghana Med J. 2017;51(2):64-77.
11. Costa Rdos S, Nogueira LT. Family support in the control of hypertension. Rev Lat Am Enfermagem. 2008;16(5):871-876. https://doi.org/10.1590/s0104-11692008000500012
12. Thomas P, Liu H, Umberson D. Family Relationships and Well-Being. Innovation in Aging. 2017;1(3):1-11. https://doi.org/10.1093/geroni/igx025
13. Cohen S. Social relationships and health. Am Psychol. 2004;59(8):676-684. https://doi.org/10.1037/0003-066x.59.8.676
14. Strom JL, Egede LE. The impact of social support on outcomes in adult patients with type 2 diabetes: a systematic review. Curr Diab Rep. 2012;12(6):769-781. https://doi.org/10.1007/s11892-012-0317-0
15. Stopford R, Winkley K, Ismail K. Social support and glycemic control in type 2 diabetes: a systematic review of observational studies. Patient Educ Couns. 2013;93(3):549-558. https://doi.org/10.1016/j.pec.2013.08.016
16. Bosworth HB, Olsen MK, Neary A, et al. Take Control of Your Blood Pressure (TCYB) study: a multifactorial tailored behavioral and educational intervention for achieving blood pressure control. Patient Educ Couns. 2008;70(3):338-347. https://doi.org/10.1016/j.pec.2007.11.014
17. Scheurer D, Choudhry N, Swanton KA, Matlin O, Shrank W. Association between different types of social support and medication adherence. Am J Manag Care. 2012;18(12):e461-e467.
18. Magrin ME, D'Addario M, Greco A, et al. Social support and adherence to treatment in hypertensive patients: a meta-analysis. Ann Behav Med. 2015;49(3):307-318. https://doi.org/10.1007/s12160-014-9663-2
19. Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339:b2535. https://doi.org/10.1136/bmj.b2535
20. Hong QN, Fàbregues S, Bartlett G, et al. The Mixed Methods Appraisal Tool (MMAT) version 2018 for information professionals and researchers. Education for Information. 2018;34(4):1-7. https://doi.org/10.3233/EFI-180221
21. Olowookere AJ, Olowookere SA, Talabi AO, et al. Perceived family support and factors influencing medication adherence among hypertensive patients attending a Nigerian tertiary hospital. Ann Trop Med Public Health. 2015;8(6):241-245.
22. Khadoura K, Shakibazadeh E, Mansournia MA, Aljeesh Y, Fotouhi A. Determining the Prevalence of and the Factors Associated with Antihypertensive Medication Non-Adherence in the Gaza Strip. Korean J Fam Med. 2021;42(2):150-158. https://doi.org/10.4082/kjfm.19.0081
23. Haidari A, Moeini M, Khosravi A. The Impact of Peer Support Program on Adherence to the Treatment Regimen in Patients with Hypertension: A Randomized Clinical Trial Study. Iran J Nurs Midwifery Res. 2017;22(6):427-430. https://doi.org/10.4103/ijnmr.ijnmr_16_16
24. Shen Y, Peng X, Wang M, et al. Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China. J Hum Hypertens. 2017;31(1):29-36. https://doi.org/10.1038/jhh.2016.8
25. Hacihasanoglu Asilar R, Yildirim A, Saglam R, Demirturk Selcuk E, Erduran Y, Sarihan O. The effect of loneliness and perceived social support on medication adherence self-efficacy in hypertensive patients: An example of Turkey. J Vasc Nurs. 2020;38(4):183-190. https://doi.org/10.1016/j.jvn.2020.07.003
26. Pladevall M, Brotons C, Gabriel R, et al. Multicenter cluster-randomized trial of a multifactorial intervention to improve antihypertensive medication adherence and blood pressure control among patients at high cardiovascular risk (the COM99 study). Circulation. 2010;122(12):1183-1191. https://doi.org/10.1161/circulationaha.109.892778
27. Uchmanowicz B, Chudiak A, Uchmanowicz I, Rosińczuk J, Froelicher ES. Factors influencing adherence to treatment in older adults with hypertension. Clin Interv Aging. 2018;13:2425-2441. https://doi.org/10.2147/cia.s182881
28. Spikes T, Higgins M, Quyyumi A, Reilly C, Pemu P, Dunbar S. The Relationship Among Health Beliefs, Depressive Symptoms, Medication Adherence, and Social Support in African Americans With Hypertension. J Cardiovasc Nurs. 2019;34(1):44-51. https://doi.org/10.1097/jcn.0000000000000519
29. Criswell TJ, Weber CA, Xu Y, Carter BL. Effect of self-efficacy and social support on adherence to antihypertensive drugs. Pharmacotherapy. 2010;30(5):432-441. https://doi.org/10.1592/phco.30.5.432
30. G/Tsadik D, Berhane Y, Worku A. Adherence to Antihypertensive Treatment and Associated Factors in Central Ethiopia. Int J Hypertens. 2020;2020:9540810. https://doi.org/10.1155/2020/9540810
31. Hatah E, Lim KP, Ali AM, Mohamed Shah N, Islahudin F. The influence of cultural and religious orientations on social support and its potential impact on medication adherence. Patient Prefer Adherence. 2015;9:589-596. https://doi.org/10.2147/ppa.s79477
32. Kurniawati ND, Wahyuni ED, Toulasik YA. Family support improves hypertensive patient drug compliance. Indian J Public Health Res Develop. 2019;10(8):2660-2665.
33. Wallston BS, Alagna SW, DeVellis BM, et al. Social support and physical health. Health Psychology. 1983;2(4):367-391. https://doi.org/10.1037/0278-6133.2.4.367
34. Kaplan RM, Hartwell SL. Differential effects of social support and social network on physiological and social outcomes in men and women with type II diabetes mellitus. Health Psychol. 1987;6(5):387-398. https://doi.org/10.1037//0278-6133.6.5.387
35. Smith EMJ. Ethnic Minorities: Life Stress, Social Support, and Mental Health Issues. The Counseling Psychologist. 1985;13(4):537-579. https://doi.org/10.1177%2F0011000085134002
36. DiMatteo MR. Social support and patient adherence to medical treatment: a meta-analysis. Health Psychol. 2004;23(2):207-218. https://doi.org/10.1037/0278-6133.23.2.207
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Jun 22, 2021
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Shahin W, Kennedy GA, Stupans I. The association between social support and medication adherence in patients with hypertension: A systematic review. Pharm Pract (Granada) [Internet]. 2021 Jun. 22 [cited 2023 Mar. 27];19(2):2300. Available from: https://www.pharmacypractice.org/index.php/pp/article/view/2300
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